1-[4-(1-Hydroxyethyl)phenyl]ethan-1-one → 2-Bromo-1-[4-(1-hydroxy-ethyl)-phenyl]ethanone

HRID 564099노트

반응식

HRID 564099 반응식
C(OC(N1CCC2C(=CC=C(C(=O)C[Br:20])C=2)C1)=O)(C)(C)C.[OH:22][CH:23]([C:25]1[CH:30]=[CH:29][C:28]([C:31](=[O:33])[CH3:32])=[CH:27][CH:26]=1)[CH3:24]>>[Br:20][CH2:32][C:31]([C:28]1[CH:29]=[CH:30][C:25]([CH:23]([OH:22])[CH3:24])=[CH:26][CH:27]=1)=[O:33]

참가 물질

3

반응물 2

HCID 125880941-[4-(1-Hydroxyethyl)phenyl]ethan-1-oneHCID 866236896-(2-Bromo-acetyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic Acid Tert-Butyl Ester

생성물 1

HCID 866236902-Bromo-1-[4-(1-hydroxy-ethyl)-phenyl]ethanone

실험 절차

2-Bromo-1-[4-(1-hydroxy-ethyl)-phenyl]-ethanone is prepared following preparation 29c from 600 mg (3.65 mmol) 1-[4-(1-hydroxy-ethyl)-phenyl]-ethanone.

출처 및 근거

ORD 기록
ord-c52dae18a2284af08d03db7cf9bbfd78
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08067590B2

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