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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 564101생성일: 2026년 10월 25일

2-Bromo-1-[4-(hydroxymethyl)phenyl]ethanone → 4-(4-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one

https://huagongshe.com/reaction/564101

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-1-[4-(hydroxymethyl)phenyl]ethanoneHCID 19798053—
반응물4-(4-Fluorobenzyloxy)-1h-pyridin-2-oneHCID 22049900—
반응물4-Benzyloxy-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 67006842—
생성물4-(4-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 58042834—

반응 단계

4-(4-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one is prepared following preparation 15b (DMSO as solvent) from 1.10 g (5.00 mmol) 4-(4-fluoro-benzyloxy)-1H-pyridin-2-one (preparation 22.1) and 1.15 g (5.00 mmol) 2-bromo-1-(4-hydroxymethylphenyl)-ethanone (preparation 15a).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08067590B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-c43f0f57e6dd4d829e5d41df5c72b4e9
출처 메모uspto-grants-2011_11