Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Amino-5-bromo-3-chlorophenyl)methanol → 2-Amino-5-bromo-3-chlorobenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Amino-5-bromo-3-chlorophenyl)methanol | HCID 67080684 | — |
| 촉매 | Manganese oxide | HCID 160959 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Amino-5-bromo-3-chlorobenzaldehyde | HCID 91666307 | 91% |
반응 단계
A mixture of (2-amino-5-bromo-3-chlorophenyl)methanol (10.0 g, 42.5 mmol) and manganese oxide (21.9 g, 255 mmol) in dichloromethane (400 mL) was stirred at room temperature overnight. The solid was filtered off, and the filtrate was concentrated to give the title compound as a light yellow solid (9.0 g, 91%), which was directly used in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434700B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-7e7701d9d0d548799f1f2084c43bcec7 |
| 출처 메모 | uspto-grants-2016_09 |