Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Amino-5-bromo-4-chlorophenyl)methanol → 2-Amino-5-bromo-4-chlorobenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Amino-5-bromo-4-chlorophenyl)methanol | HCID 67081018 | — |
| 촉매 | HCID 178418406 | HCID 178418406 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Amino-5-bromo-4-chlorobenzaldehyde | HCID 89419680 | 83.6% |
반응 단계
A mixture of (2-amino-5-bromo-4-chlorophenyl)methanol (6 g, 25.5 mmol) and manganese(IV) oxide (15.5 g, 0.178 mol) in dichloromethane (100 mL) was stirred at room temperature overnight. The solid was filtered off, and the filtrate was concentrated to give the title compound as a light yellow solid (5 g, 81%). MS (ES+) C7H5BrClNO requires: 233, 235, found: 234, 236 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434700B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-6c416bf047144bc99092021fcac746e0 |
| 출처 메모 | uspto-grants-2016_09 |