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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 564555생성일: 2026년 10월 26일

Tert-butyl 4-(3-bromobenzylidene)piperidine-1-carboxylate → Tert-butyl 4-(3-bromobenzyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/564555

반응식

참여 물질

역할이름HCID투입량
반응물Tert-butyl 4-(3-bromobenzylidene)piperidine-1-carboxylateHCID 57813409—
촉매PalladiumHCID 23938—
용매TetrahydrofuranHCID 8028—
생성물Tert-butyl 4-(3-bromobenzyl)piperidine-1-carboxylateHCID 5781336594.4%

반응 단계

To a solution of 1,1-dimethylethyl 4-[(3-bromophenyl)methylidene]-1-piperidinecarboxylate (201 mg, 0.571 mmol) in THF (1 mL) was applied onto H-Cube using 10% Pd/C at a flow rate of 1 mL/min and 1 atm H2. The mixture was concentrated to afford 0.1909 g (94%) of the title compound. LC-MS m/z 354 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08067408B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-df9fe245de054905bacedbd7e7a4ed5f
출처 메모uspto-grants-2011_11