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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 56470생성일: 2026년 10월 23일

(2-Amino-5-bromo-3-fluorophenyl)methanol → 2-Amino-5-bromo-3-fluorobenzaldehyde

https://huagongshe.com/ko/reaction/56470

반응식

참여 물질

역할이름HCID투입량
반응물(2-Amino-5-bromo-3-fluorophenyl)methanolHCID 54312525—
촉매Manganese oxideHCID 160959—
용매DichloromethaneHCID 6344—
생성물2-Amino-5-bromo-3-fluorobenzaldehydeHCID 5425145085%

반응 단계

A mixture of (2-amino-5-bromo-3-fluorophenyl)methanol (13 g, 59.4 mmol) and manganese oxide (31 g, 356.4 mmol) in dichloromethane (400 mL) was stirred at room temperature overnight. The solid was filtered off, and the filtrate was concentrated to give the title compound (11 g, 85%) as a light yellow solid, which was directly used in the next step without further purification.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09434700B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-004fce44929f4e97a083ea9f5adc78fc
출처 메모uspto-grants-2016_09