Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chloropyridin-4-amine → 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid (3-chloropyridin-4-yl)amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chloropyridin-4-amine | HCID 581853 | — |
| 반응물 | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester | HCID 54119345 | — |
| 생성물 | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid (3-chloropyridin-4-yl)amide | HCID 86756187 | 72.2% |
반응 단계
Starting from 2-ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester (0.20 g) and 4-amino-3-chloropyridine (0.15 g). Purification by column chromatography on silica eluting with 50% hexane in ethyl acetate gave the title compound (0.14 g) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06169090A |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-8717e5760ffe49bc8e92bec4d4f5d370 |
| 출처 메모 | uspto-grants-2001_01 |