Dimethylamine → 6-(N,N-Dimethylamino)-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

HRID 564772노트

반응식

HRID 564772 반응식
Cl[C:2]1[N:27]=[CH:26][C:5]2[N:6]=[CH:7][N:8]=[C:9]([NH:10][C:11]3[CH:16]=[CH:15][C:14]([S:17]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)(=[O:19])=[O:18])=[CH:13][CH:12]=3)[C:4]=2[CH:3]=1.[CH3:28][NH:29][CH3:30]>>[CH3:28][N:29]([C:2]1[N:27]=[CH:26][C:5]2[N:6]=[CH:7][N:8]=[C:9]([NH:10][C:11]3[CH:16]=[CH:15][C:14]([S:17]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)(=[O:19])=[O:18])=[CH:13][CH:12]=3)[C:4]=2[CH:3]=1)[CH3:30]

참가 물질

3

반응물 2

HCID 674DimethylamineHCID 219521656-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

생성물 1

HCID 221128426-(N,N-Dimethylamino)-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

실험 절차

Prepared according to Procedure C from 6-chloro-4-(4-phenylsulphonylanilino)-pyrido[3,4-d]pyrimidine and dimethylamine (33% aqueous solution); δH (CDCl3) 9.00 (1H,s), 8.57 (1H,s), 7.78-8.00 (6H,m), 7.70 (1H,br s) 7.45-7.65 (3H,m), 6.50 (1H,s), 3.21 (6H,s); m/z (M+1)+254.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-a808e5d3a37243f08ec98c962d8aa0e4
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06169091A

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