Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Amino-4-methoxyphenyl)methanol → 2-Amino-4-methoxybenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Amino-4-methoxyphenyl)methanol | HCID 45090899 | — |
| 촉매 | Manganese oxide | HCID 160959 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Amino-4-methoxybenzaldehyde | HCID 323503 | 35.3% |
반응 단계
A mixture of (2-amino-4-methoxyphenyl)methanol (20 g, 131.0 mmol) and manganese oxide (68 g, 786.0 mmol) in dichloromethane (300 mL) was stirred at room temperature overnight. The solid was filtered off, and the filtrate was concentrated. The residue was purified by silica gel chromatography (petroleum ether:ethyl acetate=6:1) to give the title compound (7 g, 35%) as a yellow solid. MS (ES+) C8H9NO2 requires: 151, found: 152 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434700B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-003cfd564bcb451a939941a0e045f637 |
| 출처 메모 | uspto-grants-2016_09 |