Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → Methyl N-methylindole-6-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl indole-6-carboxylate | HCID 639844 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Methyl N-methylindole-6-carboxylate | HCID 639843 | 86.9% |
반응 단계
The reaction was carried out in a manner similar to Reference Example 4 except for using 3.00 (17.1 mmol) of methyl 6-indolecarboxylate, 0.68 g (17.1 mmol) of 60% sodium hydroxide, 4.86 g (34.4 mmol) of methyl iodide and 60 ml of dimethylformamide. Thus 2.75 g (86.9%) of methyl 1-methyl-6-indolecarboxylate was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06169107A |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-f255b6cf83d24db78da4f92e4e6da3fc |
| 출처 메모 | uspto-grants-2001_01 |