Methanol → HCID 21194070, 화합물

HRID 565021노트

반응식

HRID 565021 반응식
[OH:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[C:11]([OH:13])=[O:12].S(Cl)(Cl)=O.[CH3:18]O>>[OH:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[C:11]([O:13][CH3:18])=[O:12]

참가 물질

4

반응물 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 211941991-Hydroxy-1H-indole-2-carboxylic acid

생성물 1

HCID 21194070HCID 21194070, 화합물수율 59.5%

실험 절차

The reaction was carried out in a manner similar to Reference Example 6 except for using 3.99 g (22.5 mmol) of 1-hydroxy-2-indolecarboxylic acid, 5.36 g (45.0 mmol) of thionyl chloride and 100 ml of methanol. Thus 2.56 g (59.5%) of methyl 1-hydroxy-2-indolecarboxylate was obtained.

출처 및 근거

ORD 기록
ord-c2e40e079aa542d4941a66f175ed141c
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06169107A

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