Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Phenylenediamine → 1H-Benzimidazole-2-acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Phenylenediamine | HCID 7243 | — |
| 반응물 | Ethyl cyanoacetate | HCID 7764 | — |
| 용매 | Propyl Acetate | HCID 7997 | — |
| 생성물 | 1H-Benzimidazole-2-acetonitrile | HCID 20455 | — |
반응 단계
Benzimidazole-2-acetonitrile was prepared as follows. A mixture of o-phenylenediamine (1 mole) and ethyl cyanoacetate (2 moles) was refluxed for about 30 hours, cooled, diluted with propyl acetate (225 mL), filtered, washed and dried, to provide benzimidazole-2-acetonitrile in a 60-70% yield. Benzimidazole-2-acetonitrile is also available commercially from Aldrich Chemical Company.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06169185A |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-a970094587af454482a0d3fad6c612f0 |
| 출처 메모 | uspto-grants-2001_01 |