Morpholine → 3-Amino-3-morpholinoacrylonitrile

HRID 565439노트

반응식

HRID 565439 반응식
[C:1]([CH2:3][C:4](=[NH:8])OCC)#[N:2].[NH:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1>C(O)C>[NH2:8][C:4]([N:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)=[CH:3][C:1]#[N:2]

참가 물질

4

반응물 2

HCID 8083MorpholineHCID 256188Ethyl 2-cyanoethanecarboximidate

생성물 1

HCID 27636313-Amino-3-morpholinoacrylonitrile

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

In anhydrous ethanol (10 ml) was dissolved ethyl 2-cyanoacetimidate (1.0 g), followed by addition of morpholine (0.78 g). The mixture was stirred at room temperature for 4 hours, and the separated crystals were collected by filtration. This crystal crop was used as it was in the next reaction.

후처리

  1. filtrationthe separated crystals were collected by filtration
  2. customwas in the next reaction

출처 및 근거

ORD 기록
ord-fd12486b577e4589a54a67f04c396b41
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06172102B2

반응 노트

불러오는 중…