Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | Benzenesulfonamide, 4-methyl-N-(4-nitrophenyl)- | HCID 69772 | — |
| 반응물 | HCID 178418368 | HCID 178418368 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide | HCID 22111802 | — |
반응 단계
This compound is prepared according to the procedure described in step A of Preparation 2.18, from 10 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 42.6 ml of a 2M solution of isobutylmagnesium chloride in ether, followed by 4.4 ml of bromine and 23.4 ml of triethylamine. 5.9 g of the expected product are obtained, m.p.=170° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06172239B2 |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-32a7ae720a0443be803c1c7691394291 |
| 출처 메모 | uspto-grants-2001_01 |