Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-[2-(4-Nitrophenyl)ethyl]piperidine → 4-(2-(Piperidin-1-yl)ethyl)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-[2-(4-Nitrophenyl)ethyl]piperidine | HCID 220573 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-(2-(Piperidin-1-yl)ethyl)aniline | HCID 10703400 | 100.3% |
반응 단계
In ethanol (100 ml) was dissolved 1-[2-(4-nitrophenyl)ethyl]piperidine (24.8 g), and to the mixture was added dried 10% palladium on carbon (1.24 g). Under hydrogen atmosphere, the mixture was stirred at room temperature under atmospheric pressure for 86 hours. The palladium was filtered off, and the filtrate was concentrated to give 1-[2-(4-aminophenyl)ethyl]-piperidine (21.7 g) as pale brown oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06172061B2 |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-18e902232dcb47e092700ab5db58a929 |
| 출처 메모 | uspto-grants-2001_01 |