Thionyl Chloride → 2,4-Pentadienoyl chloride, 5-phenyl-

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[CH:1](=[CH:10][C:11]([OH:13])=O)[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.S(Cl)([Cl:16])=O>>[CH:1](=[CH:10][C:11]([Cl:16])=[O:13])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 737775-Phenyl-2,4-pentadienoic acid

생성물 1

HCID 30848092,4-Pentadienoyl chloride, 5-phenyl-

반응 조건

온도: 45 °C

실험 절차

Cinnamylidene acetyl chloride was prepared by stirring approximately 17.15 gms of cinnamylidene acetic acid with 30 ml thionyl chloride in 300 ml of petroleum ether for 12 hours at room temperature. The reaction mixture was then refluxed for 4 hours in an oil bath at a temperature of approximately 40 to 50° C. The excess thionyl chloride and the petroleum ether were removed under reduced pressure. 1HNMR: 3=6.2 ppm (d, 2H), δ=6.9 ppm (q, 2H), δ=7.5 ppm (m, 5H). UV (in dichloromethane): λmax=333 nm, λmin=256 nm.

후처리

customThe excess thionyl chloride and the petroleum ether were removed under reduced pressure

출처 및 근거

ORD 기록: ord-f0f164bb30334cccbde495fdb84547e3
출처 데이터셋: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06174645B1

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