참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Tetradecylamine | HCID 16217 | — |
| 반응물 | Tetrahydrophthalic anhydride, cis- | HCID 98495 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 6-(Hydroxymethyl)-N-tetradecyl-3-cyclohexene-1-carboxamide | HCID 21266158 | 93.1% |
반응 단계
1-Tetradecylamine (3.51 g) was added to cis-4-cyclohexene-1,2-dicarboxylic anhydride (2.50 g) and stirred for 5 hours at 140° C. The reaction mixture was suspended into a mixed solution of 2-propanol (125 ml) and water (21 ml) and then sodium borohydride (3.11 g) was added thereto at room temperature. After being stirred for 67.5 hours at room temperature, the reaction mixture was acidified with dilute hydrochloric acid. The resulting solid was collected by filtration under a vacuum, washed with water, and dried, thereby yielding the entitled compound (5.38 g) as white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06174885B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_01 |
|---|
| ORD ID | ord-478abe3bf9a9404bbfcca86e0ea2e081 |
|---|
| 출처 메모 | uspto-grants-2001_01 |
|---|
