Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Chloromethyl)-1-trityl-1H-imidazole → HCID 15491432, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Chloromethyl)-1-trityl-1H-imidazole | HCID 2763176 | — |
| 반응물 | Potassium bis(trimethylsilyl)amide | HCID 3251421 | — |
| 반응물 | Methyl [(phenylmethylidene)amino]acetate | HCID 4169153 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 15491432 | HCID 15491432 | — |
반응 단계
A solution of potassium bis(trimethylsilyl)amide (11.34 g, 54 mmol) in THF (100 ml) was added dropwise to a mixture of (benzylidene-amino)-acetic acid methyl ester (3.83 g, 21.63 mmol) and 4-chloromethyl-1-trityl-1H-imidazole (21.6 g, 60.18 mmol) in THF (200 ml) at −78° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06174903B1 |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-ab5fe1fd22c94b839072267bc0325ec6 |
| 출처 메모 | uspto-grants-2001_01 |