참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 5-Aminoacenaphthene | HCID 62547 | — |
| 반응물 | 1-(Bromomethyl)-4-(1,1-dimethylethyl)benzene | HCID 87836 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-(5-acenaphthyl)-4-tert-butylbenzylamine | HCID 15480727 | — |
반응 단계
A mixture of 5-acenaphthylamine (1.0 g, 6 mmol) and triethylamine (0.76 g, 7.5 mmol) in toluene (50 mL) was stirred at 4° C., and 4-tert-butylbenzyl-bromide (1.36 g, 6 mmol) was added in slowly. The reaction mixture was stirred at 23° C. for 15 hours and precipitates formed. The precipitates (triethylamine.HBr) were filtered out; the filtrate was concentrated to dryness. Then the crude reaction mixture was purified by column chromatography (SiO2, hexane/CH2Cl2=5/1). N-(5-acenaphthyl)-4-tert-butylbenzylamine (1.67 g, an oil) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06174924B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_01 |
|---|
| ORD ID | ord-8c9ce8dc6e014aa1a6fe3202a06a5152 |
|---|
| 출처 메모 | uspto-grants-2001_01 |
|---|
