2-Chloropyridine → HCID 54335591, 화합물

HRID 566594노트

반응식

HRID 566594 반응식
[NH2:1][CH2:2][C@@H:3]([OH:6])[CH2:4][CH3:5].CC(C)([O-])C.[K+].Cl[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=1>>[N:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[NH:1][CH2:2][C@@H:3]([OH:6])[CH2:4][CH3:5]

참가 물질

4

반응물 3

HCID 79772-ChloropyridineHCID 6995554(2S)-1-Amino-2-butanolHCID 23665647Potassium tert-butoxide

생성물 1

HCID 54335591HCID 54335591, 화합물

실험 절차

(S)-1-Aminobutan-2-ol (35 millimoles), potassium tertiary butoxide (77 millimoles) and 2-chloropyridine (38.5 millimoles) were used in a similar manner to Example 1(a) to obtain the title compound, [α]D26=+10° (1.12% concentration in trichloromethane).

후처리

  1. customto obtain
  2. concentrationthe title compound, [α]D26=+10° (1.12% concentration in trichloromethane)

출처 및 근거

ORD 기록
ord-fa5fd1e63a644fcbbcac8089d249dc41
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06175012B1

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