참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Trifluoromethylphenol | HCID 67958 | — |
| 반응물 | 1,2-Benzenedicarbonitrile, 3-nitro- | HCID 162652 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-[2-(Trifluoromethyl)phenoxy]phthaionitrile | HCID 70218787 | 93.2% |
반응 단계
A reaction flask equipped with a cooling tube was loaded with 8.7 g of 3-nitrophthalonitrile, 9.4 g of 2-(trifluoromethyl)phenol, 13.8 g of anhydrous potassium carbonate and 350 ml of dimethyl sulfoxide, and the temperature was raised to 50° C. with stirring under nitrogen flow. After stirring at 50° C. for three hours, the heating was stopped. The reaction liquid was cooled and added into 500 ml of water, and the precipitated crystal was collected and dried to yield 13.5 g of the intended compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06177132B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_01 |
|---|
| ORD ID | ord-94338cd70cd04a0594a4c0519c257649 |
|---|
| 출처 메모 | uspto-grants-2001_01 |
|---|
