Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Naphthalic anhydride, 3-nitro- → 2-Tert-butyldimethylsilyoxy-5-nitro-benzo[de]isoquinoline-1,3-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Naphthalic anhydride, 3-nitro- | HCID 18194 | — |
| 반응물 | O-(tert-Butyldimethylsilyl)hydroxylamine | HCID 4691350 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 2-Tert-butyldimethylsilyoxy-5-nitro-benzo[de]isoquinoline-1,3-dione | HCID 131722278 | 85.1% |
반응 단계
O-(tert-Butyldimethyl-silyl)hydroxylamine (1.8 g, 12.3 mmol) was added to a solution of 3-nitro-1,8-naphthalic anhydride (2.0 g, 8.2 mmol) in 50 mL of pyridine. The solution was refluxed for 4 hours and concentrated in vacuo. Purification as described in Example A-1 gave 2.6 g of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06177423B1 |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-08316885c60c4f95938146a1dd7a2269 |
| 출처 메모 | uspto-grants-2001_01 |