4-Aminophenylacetonitrile → HCID 21264554, 화합물

HRID 567086노트

반응식

HRID 567086 반응식
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:11][C:12]([O:14]CC)=O.[NH2:17][C:18]1[CH:26]=[CH:25][C:21]([CH2:22][C:23]#[N:24])=[CH:20][CH:19]=1>>[C:23]([CH2:22][C:21]1[CH:25]=[CH:26][C:18]([NH:17][C:12](=[O:14])[CH2:11][C:3]2[N:2]([CH3:1])[C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=3[N:4]=2)=[CH:19][CH:20]=1)#[N:24]

참가 물질

3

반응물 2

HCID 770004-AminophenylacetonitrileHCID 12311520(1-Methyl-1H-benzoimidazol-2-yl)acetic acid ethyl ester

생성물 1

HCID 21264554HCID 21264554, 화합물수율 74.9%

실험 절차

1.14 g of ethyl 2-(1-methylbenzimidazol-2-yl)acetate and 970 mg of 4-aminobenzylcyanide were subjected to a condensation reaction to obtain 1.19 g of 4′-cyanomethyl-2-(1-methylbenzimidazol-2-yl)acetanilide.

출처 및 근거

ORD 기록
ord-273d9887a1d5449891244a8901914407
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06177454B1

반응 노트

불러오는 중…