Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Hydroxide → Isotretinoin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 1,4-Pentadien-3-ol, 3-methyl-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)- | HCID 6436846 | — |
| 반응물 | Triphenylphosphinehydrochloride | HCID 12196763 | — |
| 반응물 | Hydroxy butenolide | HCID 21773091 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Isotretinoin | HCID 5282379 | — |
반응 단계
43 g of the mixture of retinoic acids from the condensation of hydroxy butenolide, vinyl beta-ionol and triphenylphosphine hydrochloride in 10 ml of ethanol are treated with 15 g of a 50% potassium hydroxide aqueous solution, subsequently diluted to 200 mL with water, added with 30 mg of Bengal rose, then irradiated with a 18 Watt lamp for 12 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06177579B1 |
| 출처 데이터셋 | uspto-grants-2001_01 |
| ORD ID | ord-53c33f094f89499a89ea20c9541d821d |
| 출처 메모 | uspto-grants-2001_01 |