Piperazine → HCID 20150144, 화합물

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:14]3[N:15]=[C:16](Cl)[N:17]=[C:18]([N:19]4[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]4)[C:13]=3[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1.[NH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:14]3[N:15]=[C:16]([N:27]4[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]4)[N:17]=[C:18]([N:19]4[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]4)[C:13]=3[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 4837Piperazine

HCID 13043386HCID 13043386, 화합물

생성물 1

HCID 20150144HCID 20150144, 화합물

실험 절차

This compound was prepared analogous to Example 1 from 8-(4-bromophenyl-thio)-2-chloro-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 272°-275° C.) and piperazine.

출처 및 근거

ORD 기록: ord-0268606a08984fe5bb069d6665a38a86
출처 데이터셋: uspto-grants-1988_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04728646

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