Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Piperazinecarboxaldehyde → 8-(4-Fluorobenzyl-thio)-2-(N-formyl-piperazino)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Piperazinecarboxaldehyde | HCID 82191 | — |
| 반응물 | 2-Chloro-8-(4-fluorobenzyl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine | HCID 13043427 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 8-(4-Fluorobenzyl-thio)-2-(N-formyl-piperazino)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine | HCID 20150211 | — |
반응 단계
This compound was prepared analogous to Example 93 from 2-chloro-8-(4-fluorobenzyl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 192°-194° C.) and N-formyl-piperazine in dioxane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04728646 |
| 출처 데이터셋 | uspto-grants-1988_03 |
| ORD ID | ord-48beacbb029a470ba09ce7e28d5d5cbd |
| 출처 메모 | uspto-grants-1988_03 |