Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → 2-Thenoylacetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Ethyl 2-thenoate | HCID 76052 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Thenoylacetonitrile | HCID 141853 | 92.6% |
반응 단계
78.1 grams (0.5 mole) of thiophene-2-carboxylic acid ethyl ester and 30 grams (1 mole) of sodium hydride (80% suspension in white oil) were reacted with 41.5 grams (1 mole) of acetonitrile in 500 ml of dry toluene. There were obtained 70.0 grams (92.6% of theory) of 2-thiophenoylacetonitrile having a melting point of 110° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04728743 |
| 출처 데이터셋 | uspto-grants-1988_03 |
| ORD ID | ord-6134339ac3da40398099f92e3039b85c |
| 출처 메모 | uspto-grants-1988_03 |