참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2-(2-(2-Chloroethoxy)ethoxy)ethanol | HCID 78871 | — |
| 생성물 | Triethyl 2-[2-(2-hydroxy-ethoxy)ethoxy]ethylammonium chloride | HCID 13765545 | 95% |
반응 단계
An autoclave (capacity: 500 ml) was charged with 200 parts of methanol and 94.5 parts of triethylamine. After heating the mixture to 130° C., 135 parts of 2-[2-(2-chloro-ethoxy)ethoxy]ethanol was added over a period of 1 hour and the resulting mixture was heated at 130° C. for an additional 4 hours. Crystallization was performed as in Preparation 1 to obtain 205.0 parts of triethyl 2-[2-(2-hydroxy-ethoxy)ethoxy]ethylammonium chloride (yield: 95%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04729941 |
|---|
| 출처 데이터셋 | uspto-grants-1988_03 |
|---|
| ORD ID | ord-26b0fae42e79469cbdc05ee0a34b39ab |
|---|
| 출처 메모 | uspto-grants-1988_03 |
|---|
