Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4-(2-Iodoethyl)-1,2-dimethoxybenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | 3,4-Dimethoxyphenethyl methanesulfonate | HCID 11207682 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-(2-Iodoethyl)-1,2-dimethoxybenzene | HCID 597022 | 92.6% |
반응 단계
To a flask was added 21.2 g (0.078 mole) of 2-(3,4-dimethoxyphenyl)ethyl methanesulfonate and 44.65 g (0.3 mole) of sodium iodide in 420 ml of acetone. The solution was refluxed for 2 hr, poured into water, washed with brine, dried over MgSO4, and evaporated to give 21.1 g of a yellow oil. The oil was recrystallized in MeOH to give 17.1 g of product, mp 43°-46° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04729994 |
| 출처 데이터셋 | uspto-grants-1988_03 |
| ORD ID | ord-57623c082a6a4f979b0f7fd2560088e7 |
| 출처 메모 | uspto-grants-1988_03 |