2,2,3,3-Tetrafluoro-5-nitrobenzofuran → 5-Benzofuranamine, 2,2,3,3-tetrafluoro-2,3-dihydro-

HRID 568947노트

반응식

HRID 568947 반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[O:11][C:10]([F:13])([F:12])[C:9]([F:15])([F:14])[C:8]=2[CH:16]=1)([O-])=O>CO.[Pt]=O>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[O:11][C:10]([F:12])([F:13])[C:9]([F:15])([F:14])[C:8]=2[CH:16]=1

참가 물질

4

반응물 1

HCID 137849862,2,3,3-Tetrafluoro-5-nitrobenzofuran

생성물 1

HCID 137849875-Benzofuranamine, 2,2,3,3-tetrafluoro-2,3-dihydro-수율 94.4%

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

Hydrogenation of 2.15 g (0.011 mole) of 5-nitro-2,2,3,3-tetrafluorobenzofuran (prepared as in Example 1, Part A) with a catalytic amount (0.25 g) of platinum oxide in 150 ml of methanol produced 2.15 g of 5-amino-2,2,3,3-tetrafluorobenzofuran.

출처 및 근거

ORD 기록
ord-05cc794d33104c188da221d97c8f62ed
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04730062

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