Dimethylamine → HCID 20148413, 화합물
반응식
C(O[C:4]([C:6]1[CH:7]=[C:8]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14]1[CH:13]=[N:12][CH:11]=[CH:10][C:9]2=1)=[O:5])C.[CH3:19][NH:20][CH3:21]>C=C>[CH3:19][N:20]([CH3:21])[C:4]([C:6]1[CH:7]=[C:8]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14]1[CH:13]=[N:12][CH:11]=[CH:10][C:9]2=1)=[O:5]참가 물질
4
실험 절차
150 mg of 6-ethoxycarbonyl-β-carboline are heated in 5 ml of ethylene gylcol with 2 ml of dimethylamine solution for 20 hours to 100° C. After cooling, it is placed on ice, extracted with ethyl acetate and the organic phase is dried, filtered and concentrated. 50 mg of 6-dimethylaminocarbonyl-β-carboline are obtained as oil after chromatography on silica gel with methylene chloride/ethanol=10:1.
후처리
- temperatureAfter cooling
- extractionextracted with ethyl acetate
- customthe organic phase is dried
- filtrationfiltered
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-add9c74c1d444bdd96b0b82f2af42f84
- 출처 데이터셋
- uspto-grants-1988_03
- 특허 번호
- US04731358
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