Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Acetoxymethylindole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | 1H-indol-4-ylmethanol | HCID 2773457 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-Acetoxymethylindole | HCID 20132383 | — |
반응 단계
4-Hydroxymethylindole (17 g) is heated in pyridine (12 ml) with acetic anhydride (11.9 ml) for three hours on the steam bath. After dilution with ether, the reaction mixture is first shaken out with 1N hydrochloric acid, then with saturated sodium bicarbonate solution and finally with water. The ether solution is evaporated. 20 g of 4-acetoxymethylindole remains.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04731365 |
| 출처 데이터셋 | uspto-grants-1988_03 |
| ORD ID | ord-f5a6e312d5b741aaa43bf70079b5d383 |
| 출처 메모 | uspto-grants-1988_03 |