HCID 86741940, 화합물 → Ethyl 3-[4-(pyridin-3-yloxy)phenyl]propionate

HRID 569150노트

반응식

HRID 569150 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([O:7][C:8]2[CH:13]=[CH:12][C:11](/[CH:14]=[CH:15]/[C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:10][CH:9]=2)[CH:2]=1.[H][H]>C(O)C.[C].[Pd]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([O:7][C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:10][CH:9]=2)[CH:2]=1

참가 물질

5

반응물 2

HCID 86741940HCID 86741940, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 20148644Ethyl 3-[4-(pyridin-3-yloxy)phenyl]propionate수율 99%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

In 20 ml of ethanol was dissolved 2.0 g of ethyl (E)-3-[4-(pyridin-3-yloxy)phenyl]acrylate, and to the resulting solution was added 1.0 g of 5% palladium-carbon, after which the resulting mixture was stirred in a hydrogen atmosphere at room temperature for 5 hours. The reaction mixture was filtered and the filtrate thus obtained was concentrated under reduced pressure to obtain 2.0 g (yield 99%) of colorless, oily ethyl 3-[4-(pyridin-3-yloxy)phenyl]propionate.

후처리

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate thus obtained
  3. concentrationwas concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-4e1089d341f748539666e4f17d221097
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04731370

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