Salicylaldehyde → HCID 136460587, 화합물

HRID 569369노트

반응식

HRID 569369 반응식
[NH2:1][CH:2]1[C:14](=[O:15])[N:4]2[C:5]([C:11]([OH:13])=[O:12])=[C:6]([CH2:9][OH:10])[CH2:7][S:8][C@H:3]12.[CH:16]1([NH:22][CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1.[CH:29](=O)[C:30]1[C:31](=[CH:33][CH:34]=[CH:35][CH:36]=1)[OH:32]>O>[CH:23]1([NH:22][CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1.[CH:29](=[N:1][CH:2]1[C:14](=[O:15])[N:4]2[C:5]([C:11]([OH:13])=[O:12])=[C:6]([CH2:9][OH:10])[CH2:7][S:8][C@H:3]12)[C:30]1[C:31](=[CH:33][CH:34]=[CH:35][CH:36]=1)[OH:32]

참가 물질

5

반응물 3

HCID 6998SalicylaldehydeHCID 7582DicyclohexylamineHCID 129054807-Amino-3-hydroxymethyl-3-cephem-4-carboxylic Acid

생성물 1

HCID 136460587HCID 136460587, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid (9.21 g) was suspended in water (200 ml) and neutralized to pH 7.5 with dicyclohexylamine (7 g). To the resultant solution was added dropwise salicylaldehyde. (5.42 g). After stirring at ambient temperature for 2 hours, the precipitates were collected by filtration and dried to give 7-salicylideneamino-3-hydroxymethyl-3-cephem-4-carboxylic acid dicyclohexylamine salt (17.4 g).

후처리

  1. filtrationthe precipitates were collected by filtration
  2. customdried

출처 및 근거

ORD 기록
ord-aa3da91e4a7441809a11c60674fb5cb6
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04731443

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