Tetrahydrofuran → Indole-5-carboxaldehyde

HRID 569740

반응식

HRID 569740 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH2:10][OH:11])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.O1CCCC1>C(Cl)Cl.[O-2].[Mn+4].[O-2]>[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

참가 물질

5

반응물 2

HCID 8028TetrahydrofuranHCID 2773458(1H-indol-5-yl)methanol

생성물 1

HCID 589040Indole-5-carboxaldehyde

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6344Dichloromethane용매

실험 절차

51.1 g (0.347 mole) of 6c are stirred analogously to Example 1b in 1,900 ml of CH2Cl2 and 200 ml of tetrahydrofuran with 190 g (2.18 moles) of manganese(IV) oxide at 20° C. overnight.

후처리

  1. customat 20° C.
  2. customovernight

출처 및 근거

ORD 기록
ord-6951838fb0ee451590cf8f924ceb8212
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04734407

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