Water → 5-(1H-Indol-5-yl)-2,4-imidazolidinedione

HRID 569741노트

반응식

HRID 569741 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=O)=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[OH2:12].[C-:13]#[N:14].[Na+].[C:16](=[O:19])([O-])[O-].[NH4+:20].[NH4+]>C(O)C>[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]3[NH:20][C:13](=[O:12])[NH:14][C:16]3=[O:19])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

참가 물질

6

반응물 4

HCID 962WaterHCID 8929Sodium CyanideHCID 517111Ammonium CarbonateHCID 589040Indole-5-carboxaldehyde

생성물 1

HCID 201462515-(1H-Indol-5-yl)-2,4-imidazolidinedione

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

14.5 g (0.1 mole) of 6d are stirred analogously to Example 1c in ethanol and water with 7.35 g (0.15 mole) of sodium cyanide and 38.4 g (0.4 mole) of ammonium carbonate at 60° C. for 2 days.

출처 및 근거

ORD 기록
ord-e25b0594ce024e13923474de2a8ec69d
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04734407

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