참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | 2-amino-4-bromo-N-(4-bromo-2-fluorobenzyl)benzamide | HCID 14458995 | — |
| 생성물 | 7-Bromo-3-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydro-2,4-dioxoquinazoline | HCID 14459003 | — |
반응 단계
2-Amino-4-bromo-N-(4-bromo-2-fluorobenzyl)benzamide (2.90 g) and N,N'-carbonyldiimidazole (4.68 g) were dissolved in dioxane (50 ml). The solution was evaporated to give a residue, which was stirred at 150° C. for 30 minutes. After cooling, the precipitates were collected by filtration and washed with ethanol to give 7-bromo-3-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydro-2,4-dioxoquinazoline (2.92 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04734419 |
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| 출처 데이터셋 | uspto-grants-1988_03 |
|---|
| ORD ID | ord-972835d6878a434e94518b5c14195c7f |
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| 출처 메모 | uspto-grants-1988_03 |
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