Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Amino-2-(trifluoromethyl)benzimidazole → HCID 117622619, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Amino-2-(trifluoromethyl)benzimidazole | HCID 19345 | — |
| 반응물 | 2-[5-Chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid | HCID 117622549 | — |
| 생성물 | HCID 117622619 | HCID 117622619 | — |
반응 단계
68 mg (purity 94%, 0.20 mmol) of 2-[5-chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) (Example 12.1D) and 44 mg (0.22 mmol) of 2-(trifluoromethyl)-1H-benzimidazole-6-amine were reacted according to General Method 1. Yield: 63 mg (60% of theory)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434690B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-6aac64e77c8e422fbbcd7cb55ae1e4d2 |
| 출처 메모 | uspto-grants-2016_09 |