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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 570447생성일: 2026년 10월 25일

2-(Benzylsulfanyl)ethan-1-amine → 3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid (2-benzylsulfanyl-ethyl)-amide

https://huagongshe.com/reaction/570447

반응식

참여 물질

역할이름HCID투입량
반응물2-(Benzylsulfanyl)ethan-1-amineHCID 31198—
반응물3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid (2-amino-ethyl)-amideHCID 50924453—
생성물3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid (2-benzylsulfanyl-ethyl)-amideHCID 70795642—

반응 단계

This compound was prepared in an analogous manner as 3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid (2-amino-ethyl)-amide using 2-(benzylsulfanyl)ethanamine instead of tert-butyl-2-amino ethyl carbamate. LCMS (ESI) 409 (M+H) 1H NMR (400 MHz, DMSO-d6) δ ppm 11.52 (1H, br. s.) 10.33-10.38 (1H, m) 8.22 (1H, t, J=5.66 Hz) 8.00 (1H, d, J=5.47 Hz) 7.76 (1H, d, J=5.47 Hz) 7.45-7.51 (1H, m) 7.15-7.36 (5H, m) 6.82 (1H, d, J=5.47 Hz) 6.43 (1H, dd, J=3.42, 1.85 Hz) 3.75 (2H, s) 3.35-3.47 (2H, m) 2.51-2.58 (2H, m)

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09023847B2
출처 데이터셋uspto-grants-2015_05
ORD IDord-54754bc685d24f24ba454587d990cfb7
출처 메모uspto-grants-2015_05