Isopropanol → Isopropyl 5-(tetradecyloxy)furan-2-carboxylate

반응식

[CH2:1]([O:15][C:16]1[O:20][C:19]([C:21]([OH:23])=[O:22])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[CH3:24][CH:25](O)[CH3:26]>>[CH2:1]([O:15][C:16]1[O:20][C:19]([C:21]([O:23][CH:25]([CH3:26])[CH3:24])=[O:22])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

참가 물질

반응물 2

HCID 3776Isopropanol

HCID 1151755-(Tetradecyloxy)-2-furoic acid

생성물 1

HCID 49869760Isopropyl 5-(tetradecyloxy)furan-2-carboxylate

실험 절차

The title compound was prepared as described in Example 1 starting from 0.228 g (0.7 mmol) of 5-(tetradecyloxy)furan-2-carboxylic acid and 0.161 mL (2.1 mmol) of 2-propanol. MS (m/z, ES+): 366.30 (M+, 100%); 1H NMR (400 MHz, DMSO-d6) δ: 7.2 (d, 1H), 5.6 (d, 1H), 5.0 (p, 1H), 4.1 (t, 2H), 1.7 (p, 2H), 1.3-1.4 (m, 2H), 1.23 (d, 6H), 1.2 (s, 20H), 0.85 (t, 3H).

출처 및 근거

ORD 기록: ord-cee6f2131a4c46c8aff56619a929ccbf
출처 데이터셋: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09434718B2

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