6-(Difluoromethoxy)-1H-indole → 6-(difluoromethoxy)-1H-indole-3-carboxylic acid
반응식
FC(F)O[C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][CH:8]=[C:7]2[C:13]([OH:15])=[O:14].[F:17][CH:18]([F:29])[O:19]C1C=C2C(C=CN2)=CC=1>>[F:17][CH:18]([F:29])[O:19][C:12]1[CH:11]=[C:10]2[C:6]([C:7]([C:13]([OH:15])=[O:14])=[CH:8][NH:9]2)=[CH:5][CH:4]=1참가 물질
3
실험 절차
Prepared as for 5-(difluoromethoxy)-1H-indole-3-carboxylic acid (Example 6) starting with 6-difluoromethoxyindole (WO 97/45408 A1). MS (m/e) 227.
출처 및 근거
- ORD 기록
- ord-56d006d4d2214a268094888eb31046d4
- 출처 데이터셋
- uspto-grants-2016_09
- 특허 번호
- US09434724B2
반응 노트
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