O-Methylhydroxylamine → HCID 76461054, 화합물

참여 물질

역할	이름	HCID	투입량
반응물	O-Methylhydroxylamine	HCID 4113	—
반응물	2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-benzaldehyde	HCID 86657566	—
생성물	HCID 76461054	HCID 76461054	—

반응 단계

2-{3-[2-(1-{[3,5-Bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}benzaldehyde (150 mg) and O-methylhydroxylamine (24 mg) were reacted analogously to I-40 (step 4). This gave 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}benzaldehyde 0-methyloxime (169 mg).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US09434723B2
출처 데이터셋	uspto-grants-2016_09
ORD ID	ord-dcaa72989d1a4191b6410ea633880d3e
출처 메모	uspto-grants-2016_09