methyl 3-isothiocyanato-4-methylthiophene-2-carboxylate → HCID 178431853, 화합물
반응식
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([NH2:10])=[CH:9][C:4]=2[N:3]=[CH:2]1.[N:11]([C:14]1[C:18]([CH3:19])=[CH:17][S:16][C:15]=1[C:20](OC)=[O:21])=[C:12]=[S:13]>C1COCC1>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[C:20](=[O:21])[C:15]4[S:16][CH:17]=[C:18]([CH3:19])[C:14]=4[NH:11][C:12]3=[S:13])=[CH:9][C:4]=2[N:3]=[CH:2]1참가 물질
4
실험 절차
1H-benzo[d]imidazol-5-amine (0.13 g, 0.98 mmol) and methyl 3-isothiocyanato-4-methylthiophene-2-carboxylate (0.21 g, 0.98 mmol) were dissolved in 10 mL of THF. The mixture was stirred by heating under reflux over night. The solvent was removed and the product was purified by means of semi-preparative HPLC.
후처리
- temperatureby heating
- temperatureunder reflux over night
- customThe solvent was removed
- customthe product was purified by means of semi-preparative HPLC
출처 및 근거
- ORD 기록
- ord-ee12f5ef980c4ddd8587512812870033
- 출처 데이터셋
- uspto-grants-2015_05
- 특허 번호
- US09034907B2
반응 노트
불러오는 중…