Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylamine → 4-((N,N-Dimethylamino)methyl)phenylboronic acid pinacol ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | 2-(4-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 3734506 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-((N,N-Dimethylamino)methyl)phenylboronic acid pinacol ester | HCID 3460459 | — |
반응 단계
A mixture of 2-(4-(bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (200 mg, 0.673 mmol) and aqueous Me2NH (4 mL) in THF (10 mL) was stirred at room temperature overnight. It was then concentrated under reduced pressure to give the title compound. MS (m/z): 262 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434726B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-acbd8a8c17224c1387a500bd99a71009 |
| 출처 메모 | uspto-grants-2016_09 |