Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diclofensine → Tartrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diclofensine | HCID 68871 | — |
| 반응물 | 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline, L-Tartrate Salt | HCID 117729042 | — |
| 생성물 | Tartrate | HCID 119400 | — |
| 생성물 | 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline, L-Tartrate Salt | HCID 117729042 | — |
반응 단계
The L-tartrate of the (−)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline was prepared using (−)-4-(3,4-dichlorophenyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline following similar steps described for the synthesis of the (+)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline, L-tartrate salt ([α]24D −6.0° (c 0.10, methanol)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09034899B2 |
| 출처 데이터셋 | uspto-grants-2015_05 |
| ORD ID | ord-7b3423d0cb2f458388269adef5de404e |
| 출처 메모 | uspto-grants-2015_05 |