Cesium carbonate → N-(4-(2-(benzyloxy)ethoxy)-3-(trifluoromethyl)phenyl)-2-(4-(5-ethoxy-6-((4-methoxybenzyl)oxy)pyridin-3-yl)-2,6-difluorophenyl)acetamide

반응식

CC1(C)C(C)(C)OB([C:9]2[CH:10]=[CH:11][CH:12]=[N:13][CH:14]=2)O1.[CH2:16]([O:23][CH2:24][CH2:25][O:26][C:27]1[CH:32]=[CH:31][C:30]([NH:33][C:34](=[O:45])[CH2:35][C:36]2[C:41]([F:42])=[CH:40][C:39](Br)=[CH:38][C:37]=2[F:44])=[CH:29][C:28]=1[C:46]([F:49])([F:48])[F:47])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[C:50]([O-:53])([O-])=O.[Cs+].[Cs+]>O1CCOCC1.O.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].C(Cl)Cl>[CH2:16]([O:23][CH2:24][CH2:25][O:26][C:27]1[CH:32]=[CH:31][C:30]([NH:33][C:34](=[O:45])[CH2:35][C:36]2[C:41]([F:42])=[CH:40][C:39]([C:11]3[CH:12]=[N:13][C:14]([O:23][CH2:16][C:17]4[CH:22]=[CH:21][C:20]([O:53][CH3:50])=[CH:19][CH:18]=4)=[C:9]([O:26][CH2:25][CH3:24])[CH:10]=3)=[CH:38][C:37]=2[F:44])=[CH:29][C:28]=1[C:46]([F:49])([F:48])[F:47])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1