참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 3-Quinolinecarboxaldehyde | HCID 83641 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (Quinolin-3-yl)methanol | HCID 12662983 | — |
반응 단계
In a 250 mL round bottom flask, quinoline-3-carbaldehyde (1.57 g, 10 mmol) was dissolved anhydrous ethanol (20 mL). The solution was cooled to 0° C. under nitrogen. NaBH4 (420 mg, 11 mmol) was added in one portion. The mixture was stirred at room temperature for 2 hours, and quenched by addition of water (3 mL). Na2SO4 (15 g) was added. After 10 minutes, the mixture was filtered. The filtrate was evaporated to provide quinolin-3-ylmethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09040538B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_05 |
|---|
| ORD ID | ord-5cb8498e4d874eee874d8ceafcc87088 |
|---|
| 출처 메모 | uspto-grants-2015_05 |
|---|
