Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl isothiocyanatoformate → Ethyl aminon-(3-bromopyridin-2-YL)methanethiocarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl isothiocyanatoformate | HCID 85320 | — |
| 반응물 | 2-Amino-3-bromopyridine | HCID 817700 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Ethyl aminon-(3-bromopyridin-2-YL)methanethiocarbamate | HCID 59199107 | 100.1% |
반응 단계
To a solution of 2-amino-3-bromopyridine (50.0 g, 289 mmol, 1 equiv) in dichloromethane (500 mL) was added dropwise ethoxycarbonyl isothiocyanate (39.0 g, 297 mmol, 1.03 equiv) at room temperature. After 2 h, dichloromethane was removed in vacuo to provide crude ethyl [(3-bromopyridin-2-yl) carbamothioyl]carbamate (88 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434732B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-3f38827b80af4bdb9a6ae3cdfa4213f7 |
| 출처 메모 | uspto-grants-2016_09 |