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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 577874생성일: 2026년 10월 25일

N-Methoxy-N-methyl-1,3-thiazole-5-carboxamide → (5-((tert-butyldiphenylsilyloxy)methyl)-4-((2R,6S)-2,6-dimethylmorpholino)-2,3-difluorophenyl)(thiazol-5-yl)methanone

https://huagongshe.com/reaction/577874

반응식

참여 물질

역할이름HCID투입량
반응물N-Methoxy-N-methyl-1,3-thiazole-5-carboxamideHCID 25307138—
반응물(2R,6S)-4-(6-((tert-butyldiphenylsilyloxy)methyl)-2,3-difluorophenyl)-2,6-dimethylmorpholineHCID 67357593—
생성물(5-((tert-butyldiphenylsilyloxy)methyl)-4-((2R,6S)-2,6-dimethylmorpholino)-2,3-difluorophenyl)(thiazol-5-yl)methanoneHCID 86658072—

반응 단계

Starting materials: (2R,6S)-4-(6-((tert-butyldiphenylsilyloxy)methyl)-2,3-difluorophenyl)-2,6-dimethylmorpholine (Intermediate 3) and N-methoxy-N-methylthiazole-5-carboxamide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09040528B2
출처 데이터셋uspto-grants-2015_05
ORD IDord-11878e1c5f1245ab9ed0f8dee23acef0
출처 메모uspto-grants-2015_05