Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 2-Fluoro-5-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | N-Hydroxynicotinimidamide | HCID 308113 | — |
| 반응물 | 3-Cyano-4-fluorobenzoic acid | HCID 2773932 | — |
| 생성물 | 2-Fluoro-5-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile | HCID 67026066 | — |
반응 단계
The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 3-cyano-4-fluorobenzoic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ ppm 7.62-7.71 (m, 2H), 8.54-8.63 (m, 2H), 8.69 (dd, J=5.9, 2.2 Hz, 1H), 8.75 (dd, J=4.9, 1.5 Hz, 1H), 9.30 (dd, J=2.0, 1.0 Hz, 1H); MS (DCI/NH3) m/z 267 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09040568B2 |
| 출처 데이터셋 | uspto-grants-2015_05 |
| ORD ID | ord-42401b3d46a14dd196108e24c3c79447 |
| 출처 메모 | uspto-grants-2015_05 |